all Publications

Stein, B.D., Calzolari, D., Hellberg, K., Hu, Y.S., He, L., Hung, C.M., Toyama, E.Q., Ross, D.S., Lillemeier, B.F., Cantley, L.C., Yates, J.R., Shaw, R.J. Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. (2019) Cell Reports. 29(10):3331-3348.e7. DOI: 10.1016/j.celrep.2019.10.117

Katz, Z.B., Zhang, C., Quintana, A., Lillemeier, B.F., Hogan, P.G. Septins organize endoplasmic reticulum-plasma membrane junctions for STIM1-ORAI1 calcium signalling. (2019) Scientific Reports. 9(1):10839. DOI: 10.1038/s41598-019-46862-w

Xie, J., Han, X., Zhao, C., Canonigo-Balancio, A.J., Yates, J.R., Li, Y., Lillemeier, B.F., Altman, A. Phosphotyrosine-dependent interaction between the kinases PKCθ and Zap70 promotes proximal TCR signaling. (2019) Science Signaling. 12(577). DOI: 10.1126/scisignal.aar3349

Katz, Z.B., Novotná, L., Blount, A., Lillemeier, B.F. A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli. (2017) Nature Immunology. 18(1):86-95. DOI: 10.1038/ni.3631

Hu, Y.S., Cang, H., Lillemeier, B.F. Superresolution imaging reveals nanometer- and micrometer-scale spatial distributions of T-cell receptors in lymph nodes. (2016) Proceedings of the National Academy of Sciences of the United States of America. 113(26):7201-6. DOI: 10.1073/pnas.1512331113

Maity, P.C., Blount, A., Jumaa, H., Ronneberger, O., Lillemeier, B.F., Reth, M. B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation. (2015) Science Signaling. 8(394):ra93. DOI: 10.1126/scisignal.2005887

Klammt, C., Novotná, L., Li, D.T., Wolf, M., Blount, A., Zhang, K., Fitchett, J.R., Lillemeier, B.F. T cell receptor dwell times control the kinase activity of Zap70. (2015) Nature Immunology. 16(9):961-9. DOI: 10.1038/ni.3231

Heimbucher, T., Liu, Z., Bossard, C., McCloskey, R., Carrano, A.C., Riedel, C.G., Tanasa, B., Klammt, C., Fonslow, B.R., Riera, C.E., Lillemeier, B.F., Kemphues, K., Yates, J.R., O’Shea, C.C., Hunter, T., Dillin, A. The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity. (2015) Cell Metabolism. 22(1):151-63. DOI: 10.1016/j.cmet.2015.06.002

Roh, K.H., Lillemeier, B.F., Wang, F., Davis, M.M. The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lck. (2015) Proceedings of the National Academy of Sciences of the United States of America. 112(13):E1604-13. DOI: 10.1073/pnas.1503532112

Kasuboski, J.M., Sigal, Y.J., Joens, M.S., Lillemeier, B.F., Fitzpatrick, J.A. Super-resolution microscopy: a comparative treatment. (2012) Current Protocols in Cytometry. Chapter 2:Unit2.17. DOI: 10.1002/0471142956.cy0217s62

Klammt, C., Lillemeier, B.F. How membrane structures control T cell signaling. (2012) Frontiers in Immunology. 3:291. DOI: 10.3389/fimmu.2012.00291

Fitzpatrick, J.A., Lillemeier, B.F. Fluorescence correlation spectroscopy: linking molecular dynamics to biological function in vitro and in situ. (2011) Current Opinion in Structural Biology. 21(5):650-60. DOI: 10.1016/j.sbi.2011.06.006

Lillemeier, B.F., Davis, M.M. Probing the plasma membrane structure of immune cells through the analysis of membrane sheets by electron microscopy. (2011) Methods in Molecular Biology. 748:169-82. DOI: 10.1007/978-1-61779-139-0_12

Kuhns, M.S., Girvin, A.T., Klein, L.O., Chen, R., Jensen, K.D., Newell, E.W., Huppa, J.B., Lillemeier, B.F., Huse, M., Chien, Y.H., Garcia, K.C., Davis, M.M. Evidence for a functional sidedness to the alphabetaTCR. (2010) Proceedings of the National Academy of Sciences of the United States of America. 107(11):5094-9. DOI: 10.1073/pnas.1000925107

Huppa, J.B., Axmann, M., Mörtelmaier, M.A., Lillemeier, B.F., Newell, E.W., Brameshuber, M., Klein, L.O., Schütz, G.J., Davis, M.M. TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. (2010) Nature. 463(7283):963-7. DOI: 10.1038/nature08746

Lillemeier, B.F., Mörtelmaier, M.A., Forstner, M.B., Huppa, J.B., Groves, J.T., Davis, M.M. TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation. (2010) Nature Immunology. 11(1):90-6. DOI: 10.1038/ni.1832

Lillemeier, B.F., Pfeiffer, J.R., Surviladze, Z., Wilson, B.S., Davis, M.M. Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton. (2006) Proceedings of the National Academy of Sciences of the United States of America. 103(50):18992-7. DOI: 10.1073/pnas.0609009103

Huse, M., Lillemeier, B.F., Kuhns, M.S., Chen, D.S., Davis, M.M. T cells use two directionally distinct pathways for cytokine secretion. (2006) Nature Immunology. 7(3):247-55. DOI: 10.1038/ni1304

Kerr, I.M., Costa-Pereira, A.P., Lillemeier, B.F., Strobl, B. Of JAKs, STATs, blind watchmakers, jeeps and trains. (2003) FEBS Letters. 546(1):1-5.

Hilkens, C.M., Is’harc, H., Lillemeier, B.F., Strobl, B., Bates, P.A., Behrmann, I., Kerr, I.M. A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130. (2001) FEBS Lett. 505(1):87-91.

van Ham, M., van Lith, M., Lillemeier, B., Tjin, E., Grüneberg, U., Rahman, D., Pastoors, L., van Meijgaarden, K., Roucard, C., Trowsdale, J., Ottenhoff, T., Pappin, D., Neefjes, J. Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. (2000) Journal of Experimental Medicine. 191(7):1127-36.

van Ham, S.M., Tjin, E.P., Lillemeier, B.F., Grüneberg, U., van Meijgaarden, K.E., Pastoors, L., Verwoerd, D., Tulp, A., Canas, B., Rahman, D., Ottenhoff, T.H., Pappin, D.J., Trowsdale, J., Neefjes, J. HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading. (1997) Current Biology. 7(12):950-7.