all Publications

Katz, Z.B., Novotná, L., Blount, A., Lillemeier, B.F. A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli. (2017) Nat. Immunol. 18(1):86-95. DOI: 10.1038/ni.3631

Hu, Y.S., Cang, H., Lillemeier, B.F. Superresolution imaging reveals nanometer- and micrometer-scale spatial distributions of T-cell receptors in lymph nodes. (2016) Proc. Natl. Acad. Sci. U.S.A. 113(26):7201-6. DOI: 10.1073/pnas.1512331113

Maity, P.C., Blount, A., Jumaa, H., Ronneberger, O., Lillemeier, B.F., Reth, M. B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation. (2015) Sci Signal. 8(394):ra93. DOI: 10.1126/scisignal.2005887

Klammt, C., Novotná, L., Li, D.T., Wolf, M., Blount, A., Zhang, K., Fitchett, J.R., Lillemeier, B.F. T cell receptor dwell times control the kinase activity of Zap70. (2015) Nat. Immunol. 16(9):961-9. DOI: 10.1038/ni.3231

Heimbucher, T., Liu, Z., Bossard, C., McCloskey, R., Carrano, A.C., Riedel, C.G., Tanasa, B., Klammt, C., Fonslow, B.R., Riera, C.E., Lillemeier, B.F., Kemphues, K., Yates, J.R., O, C., Hunter, T., Dillin, A. The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity. (2015) Cell Metab. 22(1):151-63. DOI: 10.1016/j.cmet.2015.06.002

Roh, K.H., Lillemeier, B.F., Wang, F., Davis, M.M. The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lck. (2015) Proc. Natl. Acad. Sci. U.S.A. 112(13):E1604-13. DOI: 10.1073/pnas.1503532112

Kasuboski, J.M., Sigal, Y.J., Joens, M.S., Lillemeier, B.F., Fitzpatrick, J.A. Super-resolution microscopy: a comparative treatment. (2012) Curr Protoc Cytom. Chapter 2:Unit2.17. DOI: 10.1002/0471142956.cy0217s62

Klammt, C., Lillemeier, B.F. How membrane structures control T cell signaling. (2012) Front Immunol. 3:291. DOI: 10.3389/fimmu.2012.00291

Fitzpatrick, J.A., Lillemeier, B.F. Fluorescence correlation spectroscopy: linking molecular dynamics to biological function in vitro and in situ. (2011) Curr. Opin. Struct. Biol. 21(5):650-60. DOI: 10.1016/j.sbi.2011.06.006

Lillemeier, B.F., Davis, M.M. Probing the plasma membrane structure of immune cells through the analysis of membrane sheets by electron microscopy. (2011) Methods in molecular biology. 748:169-82. DOI: 10.1007/978-1-61779-139-0_12

Kuhns, M.S., Girvin, A.T., Klein, L.O., Chen, R., Jensen, K.D., Newell, E.W., Huppa, J.B., Lillemeier, B.F., Huse, M., Chien, Y.H., Garcia, K.C., Davis, M.M. Evidence for a functional sidedness to the alphabetaTCR. (2010) Proc. Natl. Acad. Sci. U.S.A. 107(11):5094-9. DOI: 10.1073/pnas.1000925107

Huppa, J.B., Axmann, M., Mörtelmaier, M.A., Lillemeier, B.F., Newell, E.W., Brameshuber, M., Klein, L.O., Schütz, G.J., Davis, M.M. TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. (2010) Nature. 463(7283):963-7. DOI: 10.1038/nature08746

Lillemeier, B.F., Mörtelmaier, M.A., Forstner, M.B., Huppa, J.B., Groves, J.T., Davis, M.M. TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation. (2010) Nat. Immunol. 11(1):90-6. DOI: 10.1038/ni.1832

Lillemeier, B.F., Pfeiffer, J.R., Surviladze, Z., Wilson, B.S., Davis, M.M. Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton. (2006) Proc. Natl. Acad. Sci. U.S.A. 103(50):18992-7. DOI: 10.1073/pnas.0609009103

Huse, M., Lillemeier, B.F., Kuhns, M.S., Chen, D.S., Davis, M.M. T cells use two directionally distinct pathways for cytokine secretion. (2006) Nat. Immunol. 7(3):247-55. DOI: 10.1038/ni1304

Kerr, I.M., Costa-Pereira, A.P., Lillemeier, B.F., Strobl, B. Of JAKs, STATs, blind watchmakers, jeeps and trains. (2003) FEBS Letters. 546(1):1-5.

Hilkens, C.M., Is’harc, H., Lillemeier, B.F., Strobl, B., Bates, P.A., Behrmann, I., Kerr, I.M. A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130. (2001) FEBS Lett. 505(1):87-91.

van Ham, M., van Lith, M., Lillemeier, B., Tjin, E., Grüneberg, U., Rahman, D., Pastoors, L., van Meijgaarden, K., Roucard, C., Trowsdale, J., Ottenhoff, T., Pappin, D., Neefjes, J. Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. (2000) J. Exp. Med. 191(7):1127-36.

van Ham, S.M., Tjin, E.P., Lillemeier, B.F., Grüneberg, U., van Meijgaarden, K.E., Pastoors, L., Verwoerd, D., Tulp, A., Canas, B., Rahman, D., Ottenhoff, T.H., Pappin, D.J., Trowsdale, J., Neefjes, J. HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading. (1997) Curr. Biol. 7(12):950-7.